Appalachian State University
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Effect Of Apple Peel Extract Supplementation In Skeletal Muscle Of Aged Mice

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posted on 2025-08-08, 13:08 authored by Kierstin Davis
Apple peels contain naturally occurring bioactive compounds called triterpenoids that process properties that can enhance muscle mass and function. Triterpenoids exhibit a wide range of biological functions including antioxidant, anti-microbial, anti-inflammatory, and other anticancer activities. Triterpenoids also possess anabolic properties without androgenic side effects, therefore they might be a viable treatment for promoting muscle maintenance and growth. The expanded literature review, focused on the effects of apple peel extract on muscle health, replaced my research project. The molecular pathways were examined to understand how atrophy and hypertrophy occur in skeletal muscle. Several studies discussed the effects triterpenoids paired with resistance exercise, with a high fat diet, or alone can cause skeletal muscle to increase in mass, strength by increasing IGF-1, and the PKI3/Akt/mTORC signaling pathway.

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Year Created

2020

College or School

  • The Honors College

Language

English

Access Rights

  • Open

Program of Study

Biology

Advisor

Kevin Zwetsloot

Dissertation or Thesis Type

  • Undergraduate Honors Thesis

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